Happy Birthday to Our Chairman
Well Wishes to Randal Moore our Chairman on the occasion of his Birthday from Stanford Medicine
Shadie, Stanford Medicine, Discovery Cancer Fund, Lucile Packard Children's Hospital and The Lucile Packard Foundation.
Each Extending A Happy Birthday to Ran
MFTF & Moore Family Commitment Harvard Stem Cell Institute
Stem cell research has already reshaped modern medicine. For more than five decades, hematopoietic stem cell transplantation has saved the lives of patients diagnosed with leukemia and other blood disorders. What was once pioneering science is now a clinical standard of care—demonstrating the profound and lasting impact of regenerative medicine.
Today, technological breakthroughs—including gene editing, cellular reprogramming, and advanced disease modeling—have expanded the potential of stem cells far beyond transplantation. Researchers are now leveraging these tools to understand, prevent, and treat a wide spectrum of human diseases at their biological origin.
At institutions such as the Harvard Stem Cell Institute (HSCI), scientists are harnessing stem cell biology in three fundamental ways.
Stem cells can be directed to become specific cell types, enabling the development of cell-replacement therapies.
For example, in diabetes, insulin-producing beta cells damaged by disease may be replaced with healthy cells generated from stem cells and corrected using gene-editing technologies. This approach holds promise not only for metabolic disorders, but also for neurodegenerative diseases, cardiac injury, hematologic malignancies, and other conditions where tissue loss is central to pathology. By studying how organs naturally respond to injury, researchers are identifying mechanisms that activate endogenous stem cells.
Understanding these regenerative pathways enables the development of therapies—such as targeted pharmaceuticals—that stimulate a patient’s own cells to restore function. Examples include efforts to regenerate inner ear hair cells to restore hearing, repair cardiac tissue following myocardial infarction, and promote neural recovery after injury.
Regina Uberti Executive Director of Philanthropy Moore Family Trust Foundation
Sustained progress in stem cell science requires not only technological innovation but visionary support for emerging investigators. Early-career researchers frequently generate the most transformative ideas—ideas that challenge established paradigms and expand the scientific frontier.
The Moore Family Trust Foundation proudly supports advancements in stem cell research through strategic philanthropic investment in discovery science, translational medicine, and fellowship initiatives. By funding innovative investigators and supporting the development of novel therapeutic approaches, the Foundation advances its longstanding commitment to transformative medical research.
Through disciplined stewardship and forward-looking philanthropy, the Foundation continues to invest in scientific breakthroughs that move from laboratory discovery to clinical application—expanding treatment options, restoring health, and ultimately pursuing cures.